 |
 |
|
|
| 02/04/2021 | 16:00 | Puebla FC | - | Mazatlán FC | 6:2 (3:0) | |
| 17:00 | FC Juárez | - | Cruz Azul | 0:1 (0:0) | ||
| 03/04/2021 | 16:00 | Atlas Guadalajara | - | Club Tijuana | 0:1 (0:1) | |
| 16:00 | CF Monterrey | - | Atlético San Luis | 4:1 (1:1) | ||
| 18:00 | CF América | - | Club Necaxa | 1:0 (0:0) | ||
| 04/04/2021 | 15:00 | Pumas UNAM | - | CF Pachuca | 4:4 (2:2) | |
| 15:00 | Deportivo Guadalajara | - | Santos Laguna | 5:2 (3:1) | ||
| 15:00 | Gallos Blancos | - | UANL Tigres | 1:4 (0:2) | ||
| 15:00 | Club León | - | Deportivo Toluca | 0:4 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 13 | 8 | 4 | 1 | 28:15 | 13 | 28 |
| 2 |
|
CF Monterrey | 13 | 9 | 1 | 3 | 24:14 | 10 | 28 |
| 3 |
|
Deportivo Toluca | 13 | 7 | 2 | 4 | 26:16 | 10 | 23 |
| 4 |
|
Club Tijuana | 13 | 7 | 1 | 5 | 20:13 | 7 | 22 |
| 5 |
|
CF América | 13 | 6 | 3 | 4 | 20:11 | 9 | 21 |
| 6 |
|
Mazatlán FC | 13 | 6 | 3 | 4 | 23:22 | 1 | 21 |
| 7 |
|
Atlas Guadalajara | 13 | 6 | 2 | 5 | 16:12 | 4 | 20 |
| 8 |
|
Club León | 13 | 6 | 2 | 5 | 18:24 | -6 | 20 |
| 9 |
|
Santos Laguna | 13 | 5 | 4 | 4 | 22:15 | 7 | 19 |
| 10 |
|
UANL Tigres | 13 | 5 | 3 | 5 | 19:13 | 6 | 18 |
| 11 |
|
FC Juárez | 13 | 5 | 3 | 5 | 13:16 | -3 | 18 |
| 12 |
|
Puebla FC | 13 | 6 | 0 | 7 | 24:28 | -4 | 18 |
| 13 |
|
Pumas UNAM | 13 | 4 | 4 | 5 | 20:25 | -5 | 16 |
| 14 |
|
Cruz Azul | 13 | 4 | 3 | 6 | 10:20 | -10 | 15 |
| 15 |
|
Deportivo Guadalajara | 13 | 4 | 1 | 8 | 22:24 | -2 | 13 |
| 16 |
|
Atlético San Luis | 13 | 4 | 0 | 9 | 15:29 | -14 | 12 |
| 17 |
|
Gallos Blancos | 13 | 3 | 1 | 9 | 11:25 | -14 | 10 |
| 18 |
|
Club Necaxa | 13 | 2 | 3 | 8 | 11:20 | -9 | 9 |
| Playoffs |
