| 2. Round | 13/01/2019 | Santos Laguna [U17] | - | Monarcas Morelia [U17] | 1:1 | ||||
| 3. Round | 18/01/2019 | Puebla FC [U17] | - | Santos Laguna [U17] | 0:2 | ||||
| 4. Round | 27/01/2019 | Santos Laguna [U17] | - | Deportivo Guadalajara [U17] | 1:0 | ||||
| 5. Round | 02/02/2019 | UANL Tigres [U17] | - | Santos Laguna [U17] | 0:1 | ||||
| 6. Round | 10/02/2019 | Santos Laguna [U17] | - | Club Tijuana [U17] | 1:0 | ||||
| 7. Round | 16/02/2019 | Cruz Azul [U17] | - | Santos Laguna [U17] | 0:8 | ||||
| 8. Round | 24/02/2019 | Santos Laguna [U17] | - | Deportivo Toluca [U17] | 2:1 |  |
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| 10. Round | 08/03/2019 | CD Veracruz [U17] | - | Santos Laguna [U17] | 1:0 |  |
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| 14. Round | 20/03/2019 | CF Monterrey [U17] | - | Santos Laguna [U17] | 3:2 | |
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| 12. Round | 29/03/2019 | Atlas Guadalajara [U17] | - | Santos Laguna [U17] | 3:0 | ||||
| 13. Round | 07/04/2019 | Santos Laguna [U17] | - | CF Pachuca [U17] | 3:1 | ||||
| 15. Round | 10/04/2019 | Santos Laguna [U17] | - | Gallos Blancos [U17] | 2:1 | |
Mexico