| 1. Round | 21/07/2012 | Jaguares Chiapas | - | UANL Tigres | 0:4 | ||||
| 2. Round | 28/07/2012 | CF América | - | Jaguares Chiapas | 4:2 |  |
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| 3. Round | 05/08/2012 | CF Monterrey | - | Jaguares Chiapas | 2:1 | ||||
| 4. Round | 11/08/2012 | Jaguares Chiapas | - | Atlante | 1:2 | |
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| 5. Round | 19/08/2012 | Atlas Guadalajara | - | Jaguares Chiapas | 1:1 | ||||
| 6. Round | 25/08/2012 | Jaguares Chiapas | - | Gallos Blancos (old) | 2:1 | |
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| 7. Round | 01/09/2012 | Club Tijuana | - | Jaguares Chiapas | 2:0 | ||||
| 8. Round | 15/09/2012 | Jaguares Chiapas | - | Deportivo Toluca | 2:0 | ||||
| 9. Round | 23/09/2012 | Santos Laguna | - | Jaguares Chiapas | 0:0 | ||||
| 10. Round | 29/09/2012 | Jaguares Chiapas | - | Cruz Azul | 1:0 |  |
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| 11. Round | 05/10/2012 | Monarcas Morelia | - | Jaguares Chiapas | 1:1 | ||||
| 12. Round | 07/10/2012 | Jaguares Chiapas | - | Club San Luis | 4:0 | |
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| 13. Round | 14/10/2012 | Deportivo Guadalajara | - | Jaguares Chiapas | 1:1 | |
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| 14. Round | 20/10/2012 | Jaguares Chiapas | - | Puebla FC | 2:0 | ||||
| 15. Round | 27/10/2012 | Club León | - | Jaguares Chiapas | 4:1 | |
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| 16. Round | 03/11/2012 | Jaguares Chiapas | - | Pumas UNAM | 3:0 | |
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| 17. Round | 11/11/2012 | CF Pachuca | - | Jaguares Chiapas | 2:1 |
Colombia
Mexico