| 1. Round | 06/01/2013 | UANL Tigres | - | Jaguares Chiapas | 3:0 | ||||
| 2. Round | 12/01/2013 | Jaguares Chiapas | - | CF América | 0:2 | ||||
| 3. Round | 19/01/2013 | Jaguares Chiapas | - | CF Monterrey | 1:1 | ||||
| 4. Round | 28/01/2013 | Atlante | - | Jaguares Chiapas | 4:3 | ||||
| 5. Round | 02/02/2013 | Jaguares Chiapas | - | Atlas Guadalajara | 1:2 |  |
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| 6. Round | 09/02/2013 | Gallos Blancos (old) | - | Jaguares Chiapas | 1:1 | ||||
| 7. Round | 16/02/2013 | Jaguares Chiapas | - | Club Tijuana | 2:0 | |
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| 8. Round | 24/02/2013 | Deportivo Toluca | - | Jaguares Chiapas | 2:1 | |
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| 9. Round | 02/03/2013 | Jaguares Chiapas | - | Santos Laguna | 1:3 | |
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| 10. Round | 09/03/2013 | Cruz Azul | - | Jaguares Chiapas | 1:1 | |
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| 11. Round | 16/03/2013 | Jaguares Chiapas | - | Monarcas Morelia | 1:1 | |
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| 12. Round | 31/03/2013 | Club San Luis | - | Jaguares Chiapas | 3:0 | ||||
| 13. Round | 06/04/2013 | Jaguares Chiapas | - | Deportivo Guadalajara | 3:2 | |
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| 14. Round | 14/04/2013 | Puebla FC | - | Jaguares Chiapas | 1:2 | ||||
| 15. Round | 20/04/2013 | Jaguares Chiapas | - | Club León | 2:2 | |
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| 16. Round | 28/04/2013 | Pumas UNAM | - | Jaguares Chiapas | 3:0 | ||||
| 17. Round | 04/05/2013 | Jaguares Chiapas | - | CF Pachuca | 2:1 | |
Colombia
Mexico