| 13. Round | 19/12/2020 | Sampdoria | - | FC Crotone | 3:1 | ||||
| 15. Round | 03/01/2021 | Inter | - | FC Crotone | 6:2 | ||||
| 18. Round | 17/01/2021 | FC Crotone | - | Benevento Calcio | 4:1 | ||||
| 19. Round | 23/01/2021 | ACF Fiorentina | - | FC Crotone | 2:1 | ||||
| 29. Round | 03/04/2021 | SSC Napoli | - | FC Crotone | 4:3 |  |
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| 31. Round | 17/04/2021 | FC Crotone | - | Udinese Calcio | 1:2 | ||||
| 37. Round | 16/05/2021 | Benevento Calcio | - | FC Crotone | 1:1 |
Chile