| 1. Round | 11/01/2025 | Mazatlán FC | - | FC Juárez | 1:1 |  |
|||
| 3. Round | 25/01/2025 | Mazatlán FC | - | Deportivo Toluca | 2:1 | ||||
| 4. Round | 29/01/2025 | Puebla FC | - | Mazatlán FC | 0:1 | ||||
| 6. Round | 10/02/2025 | Pumas UNAM | - | Mazatlán FC | 1:0 | ||||
| 8. Round | 22/02/2025 | Club Necaxa | - | Mazatlán FC | 3:1 | ||||
| 9. Round | 26/02/2025 | Mazatlán FC | - | CF Monterrey | 1:0 | |
|||
| 10. Round | 01/03/2025 | Mazatlán FC | - | Cruz Azul | 1:1 | ||||
| 11. Round | 09/03/2025 | CF Pachuca | - | Mazatlán FC | 1:1 | ||||
| 12. Round | 15/03/2025 | Gallos Blancos | - | Mazatlán FC | 1:0 | ||||
| 17. Round | 20/04/2025 | CF América | - | Mazatlán FC | 5:0 |
Mexico