| 4. Round | 23/09/2012 | El Tanque Sisley | - | River Plate | 1:0 | ||||
| 5. Round | 30/09/2012 | River Plate | - | Liverpool | 2:0 |  |
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| 6. Round | 07/10/2012 | River Plate | - | Montevideo Wanderers | 1:3 | ||||
| 7. Round | 13/10/2012 | River Plate | - | Progreso | 0:0 | ||||
| 8. Round | 20/10/2012 | River Plate | - | Bella Vista | 0:2 | ||||
| 9. Round | 28/10/2012 | Cerro Largo | - | River Plate | 2:2 | ||||
| 12. Round | 17/11/2012 | Danubio | - | River Plate | 0:2 |
Uruguay