| 1. Round | 06/08/2005 | Viktoria Plzeň | - | AC Sparta Praha | 1:2 |  |
|||
| 2. Round | 13/08/2005 | AC Sparta Praha | - | FK SIAD Most | 2:1 | ||||
| 3. Round | 20/08/2005 | Slovan Liberec | - | AC Sparta Praha | 2:0 | ||||
| 4. Round | 29/08/2005 | AC Sparta Praha | - | 1. FC Brno | 1:1 | ||||
| 5. Round | 10/09/2005 | AC Sparta Praha | - | Vysočina Jihlava | 2:0 | |
|||
| 7. Round | 24/09/2005 | AC Sparta Praha | - | Baník Ostrava | 0:2 | ||||
| 8. Round | 02/10/2005 | FK Teplice | - | AC Sparta Praha | 2:1 | ||||
| 9. Round | 15/10/2005 | AC Sparta Praha | - | Chmel Blsany | 5:2 | ||||
| 10. Round | 23/10/2005 | Slavia Praha | - | AC Sparta Praha | 4:1 |  |
|||
| 11. Round | 29/10/2005 | AC Sparta Praha | - | Sigma Olomouc | 1:2 | ||||
| 12. Round | 05/11/2005 | FK Jablonec 97 | - | AC Sparta Praha | 2:1 | ||||
| 13. Round | 19/11/2005 | AC Sparta Praha | - | FK Mladá Boleslav | 4:2 | ||||
| 15. Round | 03/12/2005 | AC Sparta Praha | - | FK Marila Příbram | 1:1 | ||||
| 16. Round | 12/12/2005 | FK SIAD Most | - | AC Sparta Praha | 0:3 | |
Czech Republic