| 2. Round | 13/11/2022 | Diagoras FC | - | Anagennisi Karditsa | 0:2 | ||||
| 3. Round | 21/11/2022 | Anagennisi Karditsa | - | Iraklis Larissa | 2:0 | ||||
| 5. Round | 03/12/2022 | Anagennisi Karditsa | - | Niki Volou FC | 1:0 | ||||
| 6. Round | 11/12/2022 | Apollon Lárissa | - | Anagennisi Karditsa | 0:3 | ||||
| 7. Round | 19/12/2022 | Anagennisi Karditsa | - | Thesprotos | 1:0 | ||||
| 8. Round | 22/12/2022 | Almopos Arideas | - | Anagennisi Karditsa | 1:0 | ||||
| 9. Round | 03/01/2023 | Anagennisi Karditsa | - | AEP Iraklis FC | 1:0 | ||||
| 14. Round | 11/03/2023 | AE Lárissa | - | Anagennisi Karditsa | 0:1 | ||||
| 17. Round | 03/04/2023 | Anagennisi Karditsa | - | Diagoras FC | 4:1 | ||||
| 18. Round | 06/04/2023 | Iraklis Larissa | - | Anagennisi Karditsa | 0:2 | ||||
| 19. Round | 10/04/2023 | Anagennisi Karditsa | - | PAOK Saloniki II | 1:2 | ||||
| 20. Round | 19/04/2023 | Niki Volou FC | - | Anagennisi Karditsa | 1:1 | ||||
| 22. Round | 29/04/2023 | Thesprotos | - | Anagennisi Karditsa | 0:0 | ||||
| 23. Round | 02/05/2023 | Anagennisi Karditsa | - | Almopos Arideas | 2:2 | ||||
| 24. Round | 05/05/2023 | AEP Iraklis FC | - | Anagennisi Karditsa | 1:1 |
Greece