| 1. Round | 10/07/2016 | General Díaz | - | General Caballero ZC | 0:0 | ||||
| 2. Round | 16/07/2016 | River Plate | - | General Díaz | 0:0 | ||||
| 3. Round | 19/07/2016 | General Díaz | - | Deportivo Capiatá | 0:1 | ||||
| 4. Round | 23/07/2016 | Cerro Porteño | - | General Díaz | 2:3 | ||||
| 5. Round | 29/07/2016 | General Díaz | - | Sol de América | 1:2 | ||||
| 8. Round | 21/08/2016 | General Díaz | - | Sportivo Luqueño | 1:1 | ||||
| 9. Round | 28/08/2016 | Guaraní | - | General Díaz | 1:0 | ||||
| 10. Round | 11/09/2016 | General Díaz | - | Club Olimpia | 1:2 |  |
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| 13. Round | 30/09/2016 | General Díaz | - | River Plate | 2:0 | ||||
| 15. Round | 22/10/2016 | General Díaz | - | Cerro Porteño | 1:1 | ||||
| 19. Round | 25/11/2016 | Sportivo Luqueño | - | General Díaz | 1:1 | ||||
| 20. Round | 04/12/2016 | General Díaz | - | Guaraní | 1:2 | ||||
| 21. Round | 11/12/2016 | Club Olimpia | - | General Díaz | 3:0 | |
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| 22. Round | 16/12/2016 | General Díaz | - | Club Rubio Ñu | 1:1 |
Paraguay