| 17. Round | 15/08/2010 | FK Amkar Perm | - | Spartak Vladikavkaz | 1:0 | ||||
| 18. Round | 22/08/2010 | Spartak Vladikavkaz | - | Anzhi Makhachkala | 0:0 | ||||
| 19. Round | 29/08/2010 | CSKA Moskva | - | Spartak Vladikavkaz | 2:1 | ||||
| 20. Round | 11/09/2010 | Sibir Novosibirsk | - | Spartak Vladikavkaz | 1:2 |  |
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| 21. Round | 18/09/2010 | Spartak Vladikavkaz | - | FK Rostov | 0:0 | ||||
| 22. Round | 25/09/2010 | Rubin Kazan | - | Spartak Vladikavkaz | 1:0 | |
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| 23. Round | 02/10/2010 | Spartak Vladikavkaz | - | Krylia Sovetov | 2:3 |  |
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| 25. Round | 23/10/2010 | Spartak Vladikavkaz | - | Dinamo Moskva | 0:0 | ||||
| 26. Round | 31/10/2010 | Zenit St. Petersburg | - | Spartak Vladikavkaz | 3:0 | ||||
| 27. Round | 07/11/2010 | Spartak Vladikavkaz | - | Lokomotiv Moskva | 0:0 | ||||
| 28. Round | 13/11/2010 | FK Tom Tomsk | - | Spartak Vladikavkaz | 1:1 | |
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| 29. Round | 20/11/2010 | Spartak Vladikavkaz | - | Terek Grozny | 2:1 | |
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| 30. Round | 28/11/2010 | FK Saturn | - | Spartak Vladikavkaz | 1:1 |
Uzbekistan
Russia