| 1. Round | 06/06/2022 | Rosario Central | - | Lanús | 0:0 |  |
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| 3. Round | 16/06/2022 | Rosario Central | - | Godoy Cruz | 1:0 | ||||
| 4. Round | 20/06/2022 | Vélez Sarsfield | - | Rosario Central | 2:0 | ||||
| 5. Round | 24/06/2022 | Rosario Central | - | Gimnasia de La Plata | 0:1 | ||||
| 6. Round | 04/07/2022 | Aldosivi | - | Rosario Central | 2:1 | ||||
| 9. Round | 21/07/2022 | Rosario Central | - | Newell's Old Boys | 1:0 | ||||
| 10. Round | 27/07/2022 | Arsenal de Sarandí | - | Rosario Central | 0:3 | ||||
| 11. Round | 01/08/2022 | Rosario Central | - | Central Córdoba SdE | 0:3 | ||||
| 25. Round | 14/10/2022 | Atlético Tucumán | - | Rosario Central | 1:1 |  |
Argentina