| 1. Round | 20/09/2007 | RSC Anderlecht | - | Rapid Wien | 1:1 | ||||
| 1. Round | 04/10/2007 | Rapid Wien | - | RSC Anderlecht | 0:1 | ||||
| Group G | 25/10/2007 | RSC Anderlecht | - | Hapoel Tel Aviv | 2:0 | ||||
| Group G | 08/11/2007 | Aalborg BK | - | RSC Anderlecht | 1:1 |  |
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| Group G | 06/12/2007 | RSC Anderlecht | - | Tottenham Hotspur | 1:1 |  |
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| Group G | 19/12/2007 | Getafe CF | - | RSC Anderlecht | 2:1 | |
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| 3. Round | 13/02/2008 | RSC Anderlecht | - | Girondins Bordeaux | 2:1 | ||||
| 3. Round | 21/02/2008 | Girondins Bordeaux | - | RSC Anderlecht | 1:1 | ||||
| Round of 16 | 06/03/2008 | RSC Anderlecht | - | Bayern München | 0:5 |  |
Poland