| 22. Round | 11/02/2006 | Excelsior Mouscron | - | RSC Anderlecht | 0:1 | ||||
| 23. Round | 18/02/2006 | KAA Gent | - | Excelsior Mouscron | 0:0 | ||||
| 24. Round | 25/02/2006 | Excelsior Mouscron | - | SV Zulte Waregem | 0:1 | ||||
| 25. Round | 04/03/2006 | RAA La Louviére | - | Excelsior Mouscron | 0:0 | ||||
| 26. Round | 11/03/2006 | Excelsior Mouscron | - | Cercle Brugge | 6:0 |  |
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| 27. Round | 18/03/2006 | Germinal Beerschot | - | Excelsior Mouscron | 1:0 |  |
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| 28. Round | 26/03/2006 | Excelsior Mouscron | - | KRC Genk | 1:0 | ||||
| 29. Round | 01/04/2006 | Standard Liège | - | Excelsior Mouscron | 2:1 | ||||
| 30. Round | 08/04/2006 | FC Brussels | - | Excelsior Mouscron | 0:1 | ||||
| 31. Round | 15/04/2006 | Excelsior Mouscron | - | KSV Roeselare | 0:1 | ||||
| 32. Round | 22/04/2006 | Lierse SK (old) | - | Excelsior Mouscron | 2:0 | ||||
| 33. Round | 30/04/2006 | Excelsior Mouscron | - | Sint-Truidense VV | 3:0 |
Poland