| 18. Round | 12/09/2021 | CD Magallanes | - | Coquimbo Unido | 0:0 | ||||
| 20. Round | 16/09/2021 | CD Magallanes | - | Puerto Montt | 3:0 | ||||
| 21. Round | 22/09/2021 | Rangers | - | CD Magallanes | 1:1 | ||||
| 22. Round | 27/09/2021 | CD Magallanes | - | Deportes Iquique | 2:2 | ||||
| 23. Round | 02/10/2021 | CD Magallanes | - | Barnechea | 1:1 | ||||
| 24. Round | 06/10/2021 | Cobreloa | - | CD Magallanes | 2:1 | ||||
| 25. Round | 13/10/2021 | CD Magallanes | - | Universidad de Concepción | 3:0 | ||||
| 27. Round | 23/10/2021 | CD Magallanes | - | Santa Cruz | 1:1 |
Chile