2. Round | 09/02/2021 | River Plate | - | Guaraní | 1:4 | ||||
3. Round | 15/02/2021 | Sol de América | - | River Plate | 1:1 | ||||
7. Round | 09/03/2021 | Cerro Porteño | - | River Plate | 3:0 | ||||
8. Round | 13/03/2021 | River Plate | - | Club Nacional | 0:0 | ||||
10. Round | 01/04/2021 | River Plate | - | 12 de Octubre de Itauguá | 0:2 |