| 6. Round | 09/09/2022 | UD Oliveirense | - | FC Penafiel | 1:1 | ||||
| 7. Round | 17/09/2022 | FC Penafiel | - | Moreirense FC | 1:1 | ||||
| 10. Round | 23/10/2022 | FC Penafiel | - | CD Feirense | 0:1 | ||||
| 11. Round | 29/10/2022 | CD Nacional | - | FC Penafiel | 1:1 | ||||
| 12. Round | 05/11/2022 | FC Penafiel | - | SC Farense | 0:2 | ||||
| 13. Round | 12/11/2022 | SL Benfica B | - | FC Penafiel | 1:2 |
Denmark