| 2. Round | 23/01/2022 | Lobos ULMX | - | Yalmakan FC | 0:1 | ||||
| 5. Round | 13/02/2022 | Yalmakan FC | - | Cañoneros FC | 3:0 | ||||
| 9. Round | 13/03/2022 | Yalmakan FC | - | CD Zap | 1:1 | ||||
| 10. Round | 19/03/2022 | Inter de Querétaro | - | Yalmakan FC | 0:2 | ||||
| 11. Round | 27/03/2022 | Yalmakan FC | - | Montañeses FC | 1:0 | ||||
| 12. Round | 02/04/2022 | Leviatán FC | - | Yalmakan FC | 1:3 |
Mexico