| 5. Round | 17/10/2020 | Club Irapuato | - | Pioneros de Cancún | 4:1 |  |
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| 6. Round | 25/10/2020 | Cafessa Jalisco | - | Club Irapuato | 4:3 | ||||
| 9. Round | 13/11/2020 | Club Irapuato | - | Azores de Hidalgo | 5:0 | ||||
| 11. Round | 27/11/2020 | Inter Playa | - | Club Irapuato | 2:0 | ||||
| 12. Round | 06/12/2020 | Club Irapuato | - | Club de Ciervos | 0:0 |
Mexico