| 1. Round | 08/01/2021 | Club Tijuana [U20] | - | Pumas UNAM [U20] | 4:1 | ||||
| 2. Round | 15/01/2021 | FC Juárez [U20] | - | Club Tijuana [U20] | 1:0 | ||||
| 7. Round | 21/02/2021 | UANL Tigres [U20] | - | Club Tijuana [U20] | 0:2 | ||||
| 8. Round | 28/02/2021 | CF Monterrey [U20] | - | Club Tijuana [U20] | 2:1 | ||||
| 9. Round | 03/03/2021 | Club Tijuana [U20] | - | CF América [U20] | 0:1 |
USA