| 2. Round | 23/07/2019 | Sportivo Luqueño | - | San Lorenzo | 1:3 | ||||
| 3. Round | 28/07/2019 | San Lorenzo | - | Cerro Porteño | 2:1 | ||||
| 4. Round | 03/08/2019 | Deportivo Santaní | - | San Lorenzo | 1:1 | ||||
| 5. Round | 10/08/2019 | San Lorenzo | - | Deportivo Capiatá | 1:1 | ||||
| 6. Round | 16/08/2019 | San Lorenzo | - | General Díaz | 1:1 | ||||
| 7. Round | 24/08/2019 | Guaraní | - | San Lorenzo | 3:1 | ||||
| 12. Round | 30/09/2019 | Libertad | - | San Lorenzo | 3:0 | ||||
| 13. Round | 08/10/2019 | San Lorenzo | - | Sportivo Luqueño | 2:0 | ||||
| 14. Round | 20/10/2019 | Cerro Porteño | - | San Lorenzo | 2:0 | ||||
| 15. Round | 27/10/2019 | San Lorenzo | - | Deportivo Santaní | 3:2 | ||||
| 16. Round | 31/10/2019 | Deportivo Capiatá | - | San Lorenzo | 1:1 | ||||
| 18. Round | 10/11/2019 | San Lorenzo | - | Guaraní | 0:0 | ||||
| 17. Round | 22/11/2019 | General Díaz | - | San Lorenzo | 1:1 |  |
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| 21. Round | 09/12/2019 | Club Nacional | - | San Lorenzo | 4:2 |
Paraguay