| 1. Round | 09/08/2015 | Nacional Potosí | - | Club San José | 1:0 | ||||
| 2. Round | 16/08/2015 | Club San José | - | Oriente Petrolero | 2:1 | ||||
| 3. Round | 23/08/2015 | Club San José | - | Sport Boys Warnes | 0:1 | ||||
| 4. Round | 28/08/2015 | Club San José | - | Universitario de Sucre | 2:4 | ||||
| 5. Round | 30/08/2015 | The Strongest | - | Club San José | 1:1 |  |
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| 6. Round | 09/09/2015 | Club San José | - | Real Potosí | 3:3 | ||||
| 7. Round | 12/09/2015 | Blooming | - | Club San José | 2:1 | ||||
| 8. Round | 19/09/2015 | Club San José | - | Ciclón | 1:1 | ||||
| 9. Round | 26/09/2015 | Petrolero de Yacuiba | - | Club San José | 5:2 |  |
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| 11. Round | 23/10/2015 | Jorge Wilstermann | - | Club San José | 1:1 | ||||
| 12. Round | 24/10/2015 | Club San José | - | Nacional Potosí | 3:2 | ||||
| 14. Round | 01/11/2015 | Sport Boys Warnes | - | Club San José | 2:1 |
Bolivia