| 7. Round | 15/02/2020 | Always Ready | - | Club San José | 1:2 | ||||
| 11. Round | 08/03/2020 | Club San José | - | Oriente Petrolero | 4:1 | ||||
| 13. Round | 28/11/2020 | Atlético Palmaflor | - | Club San José | 5:0 | ||||
| 14. Round | 30/11/2020 | Club San José | - | The Strongest | 1:1 | ||||
| 15. Round | 04/12/2020 | Bolívar | - | Club San José | 2:0 | ||||
| 16. Round | 07/12/2020 | Club San José | - | Real Santa Cruz | 4:1 | ||||
| 17. Round | 09/12/2020 | Royal Pari | - | Club San José | 2:0 | ||||
| 18. Round | 11/12/2020 | Club San José | - | Real Potosí | 1:2 | ||||
| 22. Round | 22/12/2020 | Club San José | - | Jorge Wilstermann | 0:2 | ||||
| 23. Round | 25/12/2020 | Club Aurora | - | Club San José | 2:0 | ||||
| 24. Round | 28/12/2020 | Oriente Petrolero | - | Club San José | 1:0 | ||||
| 25. Round | 29/12/2020 | Blooming | - | Club San José | 4:0 | ||||
| 26. Round | 31/12/2020 | Club San José | - | Atlético Palmaflor | 1:1 |  |
Bolivia