1. Round | 19/01/2008 | Club San Luis | - | UANL Tigres | 1:1 | ||||
2. Round | 27/01/2008 | Club Necaxa | - | Club San Luis | 1:1 | ||||
3. Round | 02/02/2008 | Cruz Azul | - | Club San Luis | 4:0 | ||||
4. Round | 09/02/2008 | Club San Luis | - | Deportivo Toluca | 2:0 | ||||
5. Round | 14/02/2008 | Veracruz (old) | - | Club San Luis | 1:1 | ||||
6. Round | 16/02/2008 | Club San Luis | - | CF Pachuca | 2:1 | ||||
7. Round | 24/02/2008 | Deportivo Guadalajara | - | Club San Luis | 2:2 | ||||
8. Round | 01/03/2008 | Club San Luis | - | Atlante | 2:0 | ||||
9. Round | 09/03/2008 | CF América | - | Club San Luis | 1:2 | ||||
10. Round | 15/03/2008 | Club San Luis | - | CF Monterrey | 3:1 | ||||
11. Round | 23/03/2008 | Puebla FC | - | Club San Luis | 1:2 | ||||
12. Round | 29/03/2008 | Club San Luis | - | Jaguares Chiapas | 0:2 | ||||
13. Round | 06/04/2008 | Pumas UNAM | - | Club San Luis | 2:3 | ||||
14. Round | 12/04/2008 | Club San Luis | - | UAG Tecos | 1:1 | ||||
15. Round | 20/04/2008 | Monarcas Morelia | - | Club San Luis | 1:2 | ||||
16. Round | 26/04/2008 | Club San Luis | - | Atlas Guadalajara | 0:0 | ||||
17. Round | 04/05/2008 | Santos Laguna | - | Club San Luis | 4:1 |