| 1. Round | 31/07/2021 | Budapest Honvéd | - | Debreceni VSC | 1:4 | ||||
| 2. Round | 08/08/2021 | Debreceni VSC | - | Újpest FC | 2:2 | ||||
| 3. Round | 14/08/2021 | Paksi SE | - | Debreceni VSC | 3:3 | ||||
| 4. Round | 21/08/2021 | Debreceni VSC | - | Zalaegerszegi TE | 1:2 | ||||
| 7. Round | 26/09/2021 | Kisvárda FC | - | Debreceni VSC | 2:1 | ||||
| 17. Round | 19/12/2021 | Gyirmót FC | - | Debreceni VSC | 0:0 | ||||
| 18. Round | 29/01/2022 | Debreceni VSC | - | Kisvárda FC | 0:0 | ||||
| 19. Round | 05/02/2022 | Fehérvár FC | - | Debreceni VSC | 1:2 |  |
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| 20. Round | 12/02/2022 | Debreceni VSC | - | Mezőkövesdi SE | 1:4 | ||||
| 21. Round | 20/02/2022 | Puskás FC | - | Debreceni VSC | 0:2 | ||||
| 22. Round | 27/02/2022 | Debreceni VSC | - | MTK Budapest | 1:0 |
Hungary