| 1. Round | 26/08/2012 | OFI Heraklion | - | Skoda Xanthi | 0:0 | ||||
| 2. Round | 01/09/2012 | Skoda Xanthi | - | AEK Athen | 1:0 |  |
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| 3. Round | 16/09/2012 | AO Kerkyra | - | Skoda Xanthi | 1:1 | |
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| 4. Round | 22/09/2012 | Skoda Xanthi | - | PAOK Saloniki | 0:3 | ||||
| 5. Round | 30/09/2012 | Platanias Chanion | - | Skoda Xanthi | 3:2 | ||||
| 6. Round | 07/10/2012 | Skoda Xanthi | - | Panathinaikos | 1:2 | |
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| 7. Round | 20/10/2012 | Olympiakos Piraeus | - | Skoda Xanthi | 4:0 | ||||
| 8. Round | 28/10/2012 | Veria FC | - | Skoda Xanthi | 0:0 | ||||
| 9. Round | 04/11/2012 | Skoda Xanthi | - | Levadiakos | 1:0 | ||||
| 10. Round | 10/11/2012 | PAS Giannina | - | Skoda Xanthi | 1:0 |  |
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| 11. Round | 18/11/2012 | Skoda Xanthi | - | Panthrakikos | 0:0 | |
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| 13. Round | 01/12/2012 | Skoda Xanthi | - | Asteras Tripolis | 1:1 | ||||
| 15. Round | 16/12/2012 | Aris Saloniki | - | Skoda Xanthi | 0:0 | ||||
| 16. Round | 07/01/2013 | Skoda Xanthi | - | OFI Heraklion | 3:0 | ||||
| 17. Round | 12/01/2013 | AEK Athen | - | Skoda Xanthi | 1:0 | ||||
| 18. Round | 20/01/2013 | Skoda Xanthi | - | AO Kerkyra | 0:0 |
Serbia