| 10. Round | 26/05/2021 | Chacaritas FC | - | El Nacional | 0:1 | ||||
| 14. Round | 12/06/2021 | Chacaritas FC | - | América de Quito | 1:0 |  |
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| 18. Round | 27/06/2021 | Independiente Juniors | - | Chacaritas FC | 3:2 | |
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| 23. Round | 18/07/2021 | El Nacional | - | Chacaritas FC | 1:0 | ||||
| 26. Round | 03/08/2021 | Chacaritas FC | - | Cumbayá | 0:1 |
Ecuador