| 3. Round | 19/05/2018 | Torque | - | Boston River | 0:1 | ||||
| 1. Round | 24/05/2018 | Peñarol | - | Boston River | 3:0 | ||||
| 4. Round | 27/05/2018 | Boston River | - | Defensor Sporting | 1:2 | ||||
| 5. Round | 30/05/2018 | River Plate | - | Boston River | 1:0 | ||||
| 6. Round | 03/06/2018 | Boston River | - | Progreso | 0:0 |  |
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| 7. Round | 07/06/2018 | Atenas | - | Boston River | 1:0 |
Uruguay