| 2. Round | 28/08/2011 | Sevilla FC | - | Málaga CF | 2:1 |  |
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| 3. Round | 10/09/2011 | Villarreal CF | - | Sevilla FC | 2:2 | ||||
| 5. Round | 20/09/2011 | CA Osasuna | - | Sevilla FC | 0:0 | ||||
| 6. Round | 24/09/2011 | Sevilla FC | - | Valencia CF | 1:0 | ||||
| 7. Round | 02/10/2011 | Atlético Madrid | - | Sevilla FC | 0:0 | |
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| 8. Round | 16/10/2011 | Sevilla FC | - | Sporting Gijón | 2:1 |  |
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| 9. Round | 22/10/2011 | FC Barcelona | - | Sevilla FC | 0:0 | |
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| 10. Round | 25/10/2011 | Sevilla FC | - | Racing Santander | 2:2 | ||||
| 11. Round | 31/10/2011 | Sevilla FC | - | Granada CF | 1:2 | ||||
| 12. Round | 05/11/2011 | RCD Mallorca | - | Sevilla FC | 0:0 | ||||
| 13. Round | 20/11/2011 | Sevilla FC | - | Athletic Club | 1:2 | ||||
| 17. Round | 17/12/2011 | Sevilla FC | - | Real Madrid | 2:6 | ||||
| 19. Round | 14/01/2012 | Sevilla FC | - | Espanyol Barcelona | 0:0 | ||||
| 1. Round | 21/01/2012 | Real Betis | - | Sevilla FC | 1:1 |
Uruguay
