| 22. Round | 10/09/2005 | FK Rostov | - | FK Amkar Perm | 2:0 | ||||
| 23. Round | 18/09/2005 | FK Rostov | - | Lokomotiv Moskva | 1:1 | ||||
| 24. Round | 25/09/2005 | Dinamo Moskva | - | FK Rostov | 2:1 | ||||
| 25. Round | 02/10/2005 | FK Rostov | - | Alania Vladikavkaz | 1:0 | ||||
| 26. Round | 15/10/2005 | Terek Grozny | - | FK Rostov | 2:3 | ||||
| 27. Round | 23/10/2005 | FK Rostov | - | FK Tom Tomsk | 2:0 | ||||
| 28. Round | 30/10/2005 | CSKA Moskva | - | FK Rostov | 2:1 |  |
|||
| 29. Round | 06/11/2005 | FK Rostov | - | Krylia Sovetov | 2:1 |  |
|||
| 30. Round | 19/11/2005 | Zenit St. Petersburg | - | FK Rostov | 4:2 |
Czech Republic