| 1. Round | 10/01/2021 | Deportivo Toluca | - | Gallos Blancos | 3:1 |  |
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| 8. Round | 27/02/2021 | Mazatlán FC | - | Gallos Blancos | 3:0 | ||||
| 9. Round | 04/03/2021 | Gallos Blancos | - | Deportivo Guadalajara | 2:2 | ||||
| 10. Round | 07/03/2021 | CF Monterrey | - | Gallos Blancos | 2:1 | ||||
| 11. Round | 15/03/2021 | Gallos Blancos | - | Atlético San Luis | 2:1 | ||||
| 12. Round | 21/03/2021 | Club Tijuana | - | Gallos Blancos | 3:1 | |
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| 14. Round | 12/04/2021 | Gallos Blancos | - | Santos Laguna | 1:0 |
Uruguay
Spain