| 1. Round | 18/07/2015 | MFK Ružomberok | - | MFK Skalica | 1:3 | ||||
| 2. Round | 25/07/2015 | MFK Skalica | - | MFK Zemplín Michalovce | 1:0 | ||||
| 4. Round | 07/08/2015 | MFK Skalica | - | FO ŽP Šport Podbrezová | 0:0 | ||||
| 6. Round | 22/08/2015 | MFK Skalica | - | Zlaté Moravce | 2:3 | ||||
| 7. Round | 29/08/2015 | Slovan Bratislava | - | MFK Skalica | 4:1 | ||||
| 14. Round | 25/10/2015 | MFK Skalica | - | FK Senica | 0:3 | ||||
| 15. Round | 31/10/2015 | FO ŽP Šport Podbrezová | - | MFK Skalica | 3:0 | ||||
| 17. Round | 21/11/2015 | Zlaté Moravce | - | MFK Skalica | 3:1 | ||||
| 18. Round | 28/11/2015 | MFK Skalica | - | Slovan Bratislava | 0:2 | ||||
| 19. Round | 04/12/2015 | Spartak Myjava | - | MFK Skalica | 3:0 |  |
|||
| 20. Round | 26/02/2016 | MFK Skalica | - | MŠK Žilina | 1:0 | |
|||
| 22. Round | 05/03/2016 | MFK Skalica | - | AS Trenčín | 1:2 | |
|||
| 23. Round | 12/03/2016 | MFK Ružomberok | - | MFK Skalica | 3:1 | ||||
| 29. Round | 24/04/2016 | Slovan Bratislava | - | MFK Skalica | 2:0 |
Slovakia