| 1. Round | 11/02/2022 | Arsenal de Sarandí | - | Rosario Central | 1:1 |  |
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| 2. Round | 15/02/2022 | Rosario Central | - | Vélez Sarsfield | 1:0 | |
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| 3. Round | 20/02/2022 | Boca Juniors | - | Rosario Central | 2:1 | |
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| 11. Round | 20/04/2022 | Lanús | - | Rosario Central | 3:1 | ||||
| 12. Round | 23/04/2022 | Rosario Central | - | Independiente | 3:0 | ||||
| 13. Round | 03/05/2022 | Huracán | - | Rosario Central | 2:1 | ||||
| 14. Round | 07/05/2022 | Rosario Central | - | Estudiantes | 3:1 | |
Argentina
Italy