| 1. Round | 10/08/2024 | NEC Nijmegen | - | FC Twente | 1:2 | ||||
| 2. Round | 17/08/2024 | FC Twente | - | Sparta Rotterdam | 1:1 | ||||
| 4. Round | 01/09/2024 | FC Utrecht | - | FC Twente | 2:1 | ||||
| 8. Round | 06/10/2024 | Feyenoord | - | FC Twente | 2:1 | ||||
| 10. Round | 27/10/2024 | FC Twente | - | Heracles Almelo | 5:0 | ||||
| 12. Round | 10/11/2024 | FC Twente | - | AFC Ajax | 2:2 | ||||
| 16. Round | 15/12/2024 | FC Twente | - | FC Groningen | 2:0 | ||||
| 18. Round | 12/01/2025 | FC Twente | - | Willem II | 6:2 | ||||
| 19. Round | 19/01/2025 | NAC Breda | - | FC Twente | 2:1 | ||||
| 21. Round | 02/02/2025 | Go Ahead Eagles | - | FC Twente | 2:2 | ||||
| 22. Round | 09/02/2025 | sc Heerenveen | - | FC Twente | 3:3 | ||||
| 23. Round | 16/02/2025 | FC Twente | - | RKC Waalwijk | 2:0 | ||||
| 20. Round | 23/02/2025 | FC Twente | - | NEC Nijmegen | 2:0 | ||||
| 24. Round | 01/03/2025 | FC Groningen | - | FC Twente | 1:1 | ||||
| 25. Round | 09/03/2025 | FC Twente | - | Almere City FC | 1:0 | ||||
| 26. Round | 16/03/2025 | FC Twente | - | Feyenoord | 2:6 | ||||
| 27. Round | 30/03/2025 | Heracles Almelo | - | FC Twente | 2:1 | ||||
| 28. Round | 05/04/2025 | FC Twente | - | Fortuna Sittard | 1:1 | ||||
| 31. Round | 04/05/2025 | Sparta Rotterdam | - | FC Twente | 0:2 | ||||
| 32. Round | 11/05/2025 | FC Twente | - | FC Utrecht | 2:0 |
Norway