| 1. Round | 28/08/2016 | Plaza Colonia | - | Racing | 1:1 |  |
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| 2. Round | 04/09/2016 | Nacional | - | Plaza Colonia | 3:2 | |
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| 3. Round | 10/09/2016 | Plaza Colonia | - | Rampla Juniors | 1:1 | ||||
| 4. Round | 18/09/2016 | Villa Española | - | Plaza Colonia | 2:4 | ||||
| 5. Round | 25/09/2016 | Danubio | - | Plaza Colonia | 3:0 | |
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| 6. Round | 01/10/2016 | Plaza Colonia | - | Peñarol | 0:0 | ||||
| 7. Round | 09/10/2016 | Plaza Colonia | - | CA Cerro | 2:3 | ||||
| 8. Round | 16/10/2016 | River Plate | - | Plaza Colonia | 2:1 | ||||
| 9. Round | 23/10/2016 | Plaza Colonia | - | Defensor Sporting | 0:1 | ||||
| 10. Round | 30/10/2016 | Montevideo Wanderers | - | Plaza Colonia | 0:0 | ||||
| 11. Round | 13/11/2016 | Plaza Colonia | - | Boston River | 2:2 | ||||
| 12. Round | 20/11/2016 | Plaza Colonia | - | Fénix | 2:0 | ||||
| 13. Round | 26/11/2016 | Juventud de Las Piedras | - | Plaza Colonia | 2:0 | ||||
| 14. Round | 04/12/2016 | Liverpool | - | Plaza Colonia | 1:1 | ||||
| 15. Round | 10/12/2016 | Plaza Colonia | - | Sud América | 0:3 | |
Uruguay