| 2. Round | 13/02/2016 | River Plate | - | Nacional | 0:3 | ||||
| 4. Round | 27/02/2016 | River Plate | - | Montevideo Wanderers | 1:1 | ||||
| 5. Round | 06/03/2016 | Racing | - | River Plate | 0:1 | ||||
| 6. Round | 20/03/2016 | River Plate | - | Plaza Colonia | 0:1 | ||||
| 10. Round | 30/04/2016 | River Plate | - | CA Cerro | 3:1 | ||||
| 11. Round | 08/05/2016 | Rentistas | - | River Plate | 2:1 | ||||
| 15. Round | 05/06/2016 | Villa Teresa | - | River Plate | 2:0 |
Uruguay