| 18. Round | 12/01/2025 | FC Groningen | - | Almere City FC | 0:0 | ||||
| 19. Round | 18/01/2025 | Go Ahead Eagles | - | FC Groningen | 2:1 | ||||
| 20. Round | 25/01/2025 | FC Groningen | - | sc Heerenveen | 1:0 | ||||
| 21. Round | 02/02/2025 | Sparta Rotterdam | - | FC Groningen | 1:0 | ||||
| 22. Round | 08/02/2025 | FC Groningen | - | NEC Nijmegen | 2:1 | ||||
| 23. Round | 15/02/2025 | Willem II | - | FC Groningen | 1:3 | ||||
| 24. Round | 01/03/2025 | FC Groningen | - | FC Twente | 1:1 | ||||
| 27. Round | 29/03/2025 | NAC Breda | - | FC Groningen | 1:1 |  |
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| 25. Round | 02/04/2025 | Feyenoord | - | FC Groningen | 4:1 | ||||
| 28. Round | 05/04/2025 | FC Groningen | - | PSV Eindhoven | 1:3 | ||||
| 29. Round | 13/04/2025 | FC Utrecht | - | FC Groningen | 3:1 | ||||
| 31. Round | 03/05/2025 | FC Groningen | - | RKC Waalwijk | 6:1 | |
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| 33. Round | 14/05/2025 | FC Groningen | - | AFC Ajax | 2:2 |  |
Netherlands