| 2. Round | 05/09/2020 | MVV | - | SC Cambuur | 1:7 | ||||
| 3. Round | 13/09/2020 | Telstar | - | MVV | 1:2 | ||||
| 5. Round | 25/09/2020 | MVV | - | TOP Oss | 3:0 |  |
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| 6. Round | 02/10/2020 | AZ Alkmaar (J) | - | MVV | 3:3 | ||||
| 7. Round | 10/10/2020 | MVV | - | Go Ahead Eagles | 0:2 | ||||
| 8. Round | 16/10/2020 | SBV Excelsior | - | MVV | 2:0 | ||||
| 13. Round | 20/11/2020 | MVV | - | Jong PSV | 3:3 | ||||
| 14. Round | 30/11/2020 | NEC Nijmegen | - | MVV | 2:1 | ||||
| 15. Round | 04/12/2020 | MVV | - | De Graafschap | 2:3 | ||||
| 16. Round | 12/12/2020 | FC Eindhoven | - | MVV | 4:0 | ||||
| 17. Round | 18/12/2020 | MVV | - | FC Dordrecht | 3:1 | ||||
| 18. Round | 03/01/2021 | FC Volendam | - | MVV | 0:1 | ||||
| 19. Round | 08/01/2021 | MVV | - | FC Utrecht (J) | 0:2 | ||||
| 20. Round | 15/01/2021 | Go Ahead Eagles | - | MVV | 3:0 | ||||
| 32. Round | 05/04/2021 | Jong PSV | - | MVV | 3:1 | ||||
| 34. Round | 16/04/2021 | TOP Oss | - | MVV | 2:2 | ||||
| 36. Round | 30/04/2021 | MVV | - | FC Volendam | 2:2 | ||||
| 37. Round | 07/05/2021 | NAC Breda | - | MVV | 2:0 | ||||
| 38. Round | 12/05/2021 | MVV | - | FC Den Bosch | 3:1 |
Belgium