| 1. Round | 18/09/2021 | Lobos Huerta | - | Club Calor | 2:1 | ||||
| 2. Round | 26/09/2021 | Aguacateros CDU | - | Lobos Huerta | 6:1 | ||||
| 4. Round | 10/10/2021 | Huracanes Izcalli | - | Lobos Huerta | 0:3 | ||||
| 6. Round | 16/10/2021 | Lobos Huerta | - | Club de Ciervos | 2:2 | ||||
| 7. Round | 22/10/2021 | Alebrijes de Oaxaca II | - | Lobos Huerta | 4:0 | ||||
| 9. Round | 06/11/2021 | Lobos Huerta | - | Aguacateros CDU | 0:2 | ||||
| 10. Round | 10/11/2021 | Guerreros Xico | - | Lobos Huerta | 1:4 | ||||
| 11. Round | 14/11/2021 | Lobos Huerta | - | Huracanes Izcalli | 4:2 | ||||
| 12. Round | 21/11/2021 | CD Cuautla | - | Lobos Huerta | 1:1 | ||||
| 14. Round | 04/12/2021 | Lobos Huerta | - | Alebrijes de Oaxaca II | 2:4 |  |
Mexico