| 1. Round | 21/07/2018 | Santos Laguna [U15] | - | Club Necaxa [U15] | 3:1 |  |
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| 3. Round | 04/08/2018 | Santos Laguna [U15] | - | UANL Tigres [U15] | 1:1 | |
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| 4. Round | 11/08/2018 | Club León [U15] | - | Santos Laguna [U15] | 1:0 | |
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| 5. Round | 18/08/2018 | Santos Laguna [U15] | - | Monarcas Morelia [U15] | 1:1 | ||||
| 7. Round | 01/09/2018 | Santos Laguna [U15] | - | CF Monterrey [U15] | 2:2 | ||||
| 8. Round | 08/09/2018 | Gallos Blancos [U15] | - | Santos Laguna [U15] | 4:3 | ||||
| 2. Round | 18/09/2018 | Deportivo Guadalajara [U15] | - | Santos Laguna [U15] | 1:2 | ||||
| 10. Round | 22/09/2018 | Club Necaxa [U15] | - | Santos Laguna [U15] | 1:0 | ||||
| 17. Round | 10/11/2018 | Santos Laguna [U15] | - | Gallos Blancos [U15] | 1:1 |
Mexico