| 1. Round | 11/09/2021 | PSV Eindhoven [U18] | - | PEC Zwolle [U18] | 0:0 | ||||
| 3. Round | 18/09/2021 | AZ Alkmaar [U18] | - | PEC Zwolle [U18] | 1:0 | ||||
| 4. Round | 25/09/2021 | PEC Zwolle [U18] | - | AFC Ajax [U18] | 0:3 | ||||
| 6. Round | 16/10/2021 | sc Heerenveen [U18] | - | PEC Zwolle [U18] | 3:2 | ||||
| 7. Round | 23/10/2021 | PEC Zwolle [U18] | - | Feyenoord [U18] | 2:3 | ||||
| 13. Round | 11/12/2021 | AFC Ajax [U18] | - | PEC Zwolle [U18] | 3:3 |
Netherlands