| 4. Round | 07/06/2018 | Houston Dynamo | - | NTX Rayados | 5:0 |  |
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| Round of 16 | 19/06/2018 | Houston Dynamo | - | Minnesota United FC | 1:0 | ||||
| Quarter-finals | 19/07/2018 | Houston Dynamo | - | Sporting Kansas City | 4:2 | ||||
| Semi-finals | 09/08/2018 | Houston Dynamo | - | Los Angeles FC | 7:6 pso | |
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| Final | 27/09/2018 | Houston Dynamo | - | Philadelphia Union | 3:0 |
USA
Mexico