| 19. Round | 13/02/2000 | Panachaiki GE | - | Aris Saloniki | 1:2 | ||||
| 20. Round | 19/02/2000 | Aris Saloniki | - | AO Proodeftiki | 2:1 | ||||
| 21. Round | 26/02/2000 | Panionios GSS | - | Aris Saloniki | 1:3 | ||||
| 22. Round | 04/03/2000 | Aris Saloniki | - | Apollon Smyrnis | 2:1 | ||||
| 24. Round | 18/03/2000 | Aris Saloniki | - | AO Trikala | 3:3 |  |
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| 25. Round | 24/03/2000 | Aris Saloniki | - | AEK Athen | 1:1 | ||||
| 26. Round | 01/04/2000 | PAOK Saloniki | - | Aris Saloniki | 3:2 | |
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| 29. Round | 21/04/2000 | Aris Saloniki | - | Iraklis Saloniki | 2:1 | ||||
| 30. Round | 02/05/2000 | Paniliakos Pyrgos | - | Aris Saloniki | 1:2 | ||||
| 31. Round | 07/05/2000 | Aris Saloniki | - | Olympiakos Piraeus | 0:1 | |
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| 33. Round | 20/05/2000 | PS Kalamata | - | Aris Saloniki | 5:2 | ||||
| 34. Round | 27/05/2000 | Aris Saloniki | - | OFI Heraklion | 3:1 |
Greece