| 3. Round | 30/09/2000 | Panathinaikos | - | Aris Saloniki | 2:2 | ||||
| 4. Round | 31/10/2000 | Aris Saloniki | - | PAOK Saloniki | 4:0 | ||||
| 5. Round | 04/11/2000 | Skoda Xanthi | - | Aris Saloniki | 1:0 | ||||
| 6. Round | 11/11/2000 | Aris Saloniki | - | Iraklis Saloniki | 0:2 | ||||
| 9. Round | 02/12/2000 | Aris Saloniki | - | Ionikos Nikea | 0:0 | ||||
| 10. Round | 09/12/2000 | AEK Athen | - | Aris Saloniki | 3:1 |  |
|||
| 11. Round | 16/12/2000 | Aris Saloniki | - | Panachaiki GE | 0:0 | ||||
| 12. Round | 02/01/2001 | PS Kalamata | - | Aris Saloniki | 1:1 | ||||
| 15. Round | 20/01/2001 | Olympiakos Piraeus | - | Aris Saloniki | 4:1 | |
|||
| 16. Round | 26/01/2001 | Aris Saloniki | - | OFI Heraklion | 2:0 | ||||
| 17. Round | 03/02/2001 | Paniliakos Pyrgos | - | Aris Saloniki | 1:2 |  |
|||
| 20. Round | 24/02/2001 | Aris Saloniki | - | Skoda Xanthi | 1:0 | ||||
| 21. Round | 02/03/2001 | Iraklis Saloniki | - | Aris Saloniki | 1:2 | ||||
| 22. Round | 10/03/2001 | Athinaikos | - | Aris Saloniki | 2:0 | ||||
| 26. Round | 19/04/2001 | Panachaiki GE | - | Aris Saloniki | 4:1 | ||||
| 27. Round | 28/04/2001 | Aris Saloniki | - | PS Kalamata | 3:2 | |
Greece