| 3. Round | 01/08/2015 | FK Senica | - | MFK Skalica | 2:1 | ||||
| 10. Round | 22/09/2015 | MFK Skalica | - | FC DAC 1904 | 2:2 | ||||
| 11. Round | 26/09/2015 | AS Trenčín | - | MFK Skalica | 3:0 | ||||
| 13. Round | 18/10/2015 | MFK Zemplín Michalovce | - | MFK Skalica | 3:1 | ||||
| 16. Round | 06/11/2015 | Spartak Trnava | - | MFK Skalica | 2:1 | ||||
| 20. Round | 26/02/2016 | MFK Skalica | - | MŠK Žilina | 1:0 |  |
|||
| 21. Round | 02/03/2016 | FC DAC 1904 | - | MFK Skalica | 1:0 | ||||
| 22. Round | 05/03/2016 | MFK Skalica | - | AS Trenčín | 1:2 | ||||
| 25. Round | 02/04/2016 | FK Senica | - | MFK Skalica | 2:2 | |
|||
| 26. Round | 09/04/2016 | MFK Skalica | - | FO ŽP Šport Podbrezová | 2:1 | |
 |
||
| 27. Round | 16/04/2016 | Spartak Trnava | - | MFK Skalica | 5:1 | |
|
||
| 28. Round | 19/04/2016 | MFK Skalica | - | Zlaté Moravce | 1:0 | ||||
| 29. Round | 24/04/2016 | Slovan Bratislava | - | MFK Skalica | 2:0 | ||||
| 30. Round | 01/05/2016 | MFK Skalica | - | Spartak Myjava | 1:2 | |
|||
| 31. Round | 06/05/2016 | MŠK Žilina | - | MFK Skalica | 1:0 |
Slovakia