| 1. Round | 16/09/2000 | Ionikos Nikea | - | Athinaikos | 1:0 | ||||
| 2. Round | 23/09/2000 | Athinaikos | - | AEK Athen | 0:3 | ||||
| 3. Round | 30/09/2000 | Panachaiki GE | - | Athinaikos | 3:1 |  |
|||
| 4. Round | 28/10/2000 | Athinaikos | - | PS Kalamata | 3:2 | ||||
| 5. Round | 04/11/2000 | PAS Giannina | - | Athinaikos | 3:1 | ||||
| 6. Round | 10/11/2000 | Athinaikos | - | Panionios GSS | 2:0 | |
|||
| 7. Round | 18/11/2000 | Aris Saloniki | - | Athinaikos | 2:0 | ||||
| 9. Round | 03/12/2000 | Athinaikos | - | Paniliakos Pyrgos | 1:1 | ||||
| 10. Round | 09/12/2000 | Panathinaikos | - | Athinaikos | 1:0 | ||||
| 24. Round | 31/03/2001 | Paniliakos Pyrgos | - | Athinaikos | 3:0 | ||||
| 25. Round | 07/04/2001 | Athinaikos | - | Panathinaikos | 0:4 | ||||
| 26. Round | 21/04/2001 | PAOK Saloniki | - | Athinaikos | 3:1 | ||||
| 27. Round | 28/04/2001 | Athinaikos | - | Skoda Xanthi | 2:2 | ||||
| 28. Round | 05/05/2001 | Iraklis Saloniki | - | Athinaikos | 4:2 | ||||
| 29. Round | 19/05/2001 | Olympiakos Piraeus | - | Athinaikos | 1:0 |
Greece