| 1. Round | 13/08/1999 | PSV Eindhoven | - | MVV | 4:1 | ||||
| 4. Round | 10/09/1999 | MVV | - | SC Cambuur | 1:1 | ||||
| 5. Round | 17/09/1999 | FC Den Bosch | - | MVV | 1:1 | ||||
| 6. Round | 30/09/1999 | MVV | - | sc Heerenveen | 1:3 |  |
|||
| 7. Round | 09/10/1999 | De Graafschap | - | MVV | 2:1 | ||||
| 9. Round | 15/10/1999 | MVV | - | FC Utrecht | 4:1 | ||||
| 10. Round | 22/10/1999 | Willem II | - | MVV | 1:0 | ||||
| 11. Round | 30/10/1999 | MVV | - | Fortuna Sittard | 1:0 | |
|||
| 12. Round | 05/11/1999 | MVV | - | AZ Alkmaar | 3:4 | ||||
| 12. Round | 18/11/1999 | MVV | - | Feyenoord | 3:3 | ||||
| 18. Round | 31/01/2000 | MVV | - | Roda JC Kerkrade | 0:0 | ||||
| 19. Round | 03/02/2000 | FC Utrecht | - | MVV | 2:0 | ||||
| 23. Round | 25/02/2000 | Feyenoord | - | MVV | 3:0 | ||||
| 24. Round | 03/03/2000 | SC Cambuur | - | MVV | 2:2 | |
|||
| 25. Round | 10/03/2000 | MVV | - | De Graafschap | 0:2 | ||||
| 26. Round | 17/03/2000 | sc Heerenveen | - | MVV | 3:1 | ||||
| 28. Round | 31/03/2000 | MVV | - | Vitesse | 0:2 | ||||
| 30. Round | 14/04/2000 | MVV | - | RKC Waalwijk | 0:1 | ||||
| 31. Round | 20/04/2000 | AZ Alkmaar | - | MVV | 2:0 | |
|||
| 33. Round | 06/05/2000 | AFC Ajax | - | MVV | 1:0 | |
|||
| 34. Round | 13/05/2000 | MVV | - | Willem II | 1:1 |
Netherlands