| Quarter-finals | 25/11/2021 | Pumas UNAM | - | CF América | 0:0 |  |
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| Quarter-finals | 28/11/2021 | CF América | - | Pumas UNAM | 1:3 |
| Quarter-finals | 25/11/2021 | Pumas UNAM | - | CF América | 0:0 | |
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| Quarter-finals | 28/11/2021 | CF América | - | Pumas UNAM | 1:3 |
| Miguel Arturo Layún Prado | |
| Born: | 25.06.1988 |
| Place of birth: |
Córdoba, Veracruz, 
Mexico |
| Nationality: |
Mexico
Spain |
| Height: | 183 cm |
| Weight: | 75 kg |
| Position(s): | Right Back Left Back |
| Foot: | both |