| 1. Round | 19/01/2019 | Real Potosí | - | CD Guabirá | 3:1 | ||||
| 2. Round | 27/01/2019 | Real Potosí | - | Oriente Petrolero | 1:1 | ||||
| 3. Round | 30/01/2019 | The Strongest | - | Real Potosí | 4:1 | ||||
| 4. Round | 03/02/2019 | Real Potosí | - | Sport Boys Warnes | 2:1 |  |
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| 5. Round | 07/02/2019 | Jorge Wilstermann | - | Real Potosí | 5:0 | ||||
| 6. Round | 11/02/2019 | Real Potosí | - | Destroyers | 3:2 | |
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| 7. Round | 17/02/2019 | Club San José | - | Real Potosí | 2:2 | ||||
| 8. Round | 20/02/2019 | Real Potosí | - | Nacional Potosí | 1:3 | ||||
| 9. Round | 23/02/2019 | Blooming | - | Real Potosí | 5:3 | |
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| 10. Round | 28/02/2019 | Real Potosí | - | Bolívar | 2:2 | |
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| 11. Round | 09/03/2019 | Always Ready | - | Real Potosí | 3:1 | ||||
| 14. Round | 31/03/2019 | CD Guabirá | - | Real Potosí | 2:1 | ||||
| 15. Round | 04/04/2019 | Oriente Petrolero | - | Real Potosí | 2:1 | ||||
| 20. Round | 27/04/2019 | Real Potosí | - | Club San José | 2:1 | ||||
| 21. Round | 01/05/2019 | Nacional Potosí | - | Real Potosí | 0:1 | |
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| 23. Round | 11/05/2019 | Bolívar | - | Real Potosí | 4:3 | ||||
| 24. Round | 15/05/2019 | Real Potosí | - | Always Ready | 2:1 | ||||
| 25. Round | 19/05/2019 | Club Aurora | - | Real Potosí | 3:2 | ||||
| 26. Round | 25/05/2019 | Real Potosí | - | Royal Pari | 3:1 |
Bolivia