| 1. Round | 28/07/2012 | Libertad | - | Club Nacional | 1:0 | ||||
| 2. Round | 03/08/2012 | Tacuary | - | Libertad | 1:1 | ||||
| 3. Round | 12/08/2012 | Libertad | - | Guaraní | 0:0 | ||||
| 4. Round | 19/08/2012 | Club Olimpia | - | Libertad | 2:2 |  |
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| 5. Round | 25/08/2012 | Libertad | - | Sol de América | 1:1 | |
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| 6. Round | 29/08/2012 | Sportivo Carapeguá | - | Libertad | 2:0 | ||||
| 7. Round | 02/09/2012 | Libertad | - | Club Rubio Ñu | 3:0 | ||||
| 10. Round | 30/09/2012 | Libertad | - | Cerro de Franco | 3:0 | |
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| 11. Round | 07/10/2012 | Sportivo Luqueño | - | Libertad | 0:2 | ||||
| 12. Round | 20/10/2012 | Club Nacional | - | Libertad | 1:2 | |
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| 13. Round | 27/10/2012 | Libertad | - | Tacuary | 2:2 | ||||
| 14. Round | 30/10/2012 | Guaraní | - | Libertad | 0:2 | ||||
| 15. Round | 03/11/2012 | Libertad | - | Club Olimpia | 1:1 | |
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| 16. Round | 09/11/2012 | Sol de América | - | Libertad | 0:0 | ||||
| 17. Round | 17/11/2012 | Libertad | - | Sportivo Carapeguá | 2:1 | ||||
| 18. Round | 21/11/2012 | Club Rubio Ñu | - | Libertad | 2:7 | ||||
| 19. Round | 25/11/2012 | Libertad | - | Cerro Porteño | 1:0 | |
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| 20. Round | 30/11/2012 | Independiente CG | - | Libertad | 0:5 |  |
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| 21. Round | 07/12/2012 | Cerro de Franco | - | Libertad | 0:1 | |
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| 22. Round | 16/12/2012 | Libertad | - | Sportivo Luqueño | 2:0 | |
Paraguay